USCAP Liver Pathology: Essentials of Daily Practice 2023

Original release date: November 28, 2023

Course Description
Liver biopsies are a common specimen in most surgical pathology practices. Liver biopsy interpretation is challenging because many liver diseases manifest overlapping histological features. A systematic pattern-based approach facilitates identification of subtle features that help to narrow the differential diagnoses, correlate findings with clinical data, and provide a meaningful report. This course reviews best practices in assessment and reporting of hepatitis biopsies, guides learners through the spectrum of possible diseases that may present with biliary pattern of injury, provides a comprehensive review of hepatocellular carcinoma, and discusses a systematic and practical approach on how to work up mesenchymal tumors of the liver.

Learning Objectives
Upon completion of this educational activity, learners will be able to:

• Recognize hepatic, lobular, biliary and vascular patterns of liver injury, and use histological clues and clinical data to formulate a meaningful diagnosis
• Diagnose hepatocellular, biliary and mesenchymal liver tumors, and differentiate between benign and malignant lesions as well as their mimics
• Diagnose common post-transplant pathologies in allograft biopsies
• Recognize subtle histological findings in liver biopsies that appear to be near normal