ASN Kidney Week 2024 – Advances in Research Conference – Genome Engineering and RNA-Based Therapeutics From Bench to Potentially Curative Medicines

Kidney Week 2024: Early Programs

ASN Kidney Week 2024 – Critical Care Nephrology 2024 Update

Each Early Program addresses a specific topic in nephrology and requires separate registration from the Annual Meeting.

• • Advances in Research Conference – Genome Engineering and RNA-Based Therapeutics: From Bench to Potentially Curative Medicines

    Advances in Research Conference – Genome Engineering and RNA-Based Therapeutics: From Bench to Potentially Curative Medicines

    October 23, 2024 | 07:00 AM PDT – 05:10 PM PDT

    Location: Room 6A, Convention Center

    Session Description

    This program showcases cutting-edge advances in gene therapy, genome and epigenome editing, and RNA-based therapeutics. Lectures highlight recent technological advances, the current toolbox available to clinicians, and major clinical breakthroughs, with an eye toward potential application to the treatment of kidney diseases.

    Session Objectives

    Upon completion of this program, the participant will be able to: 1) describe state-of-the-art genome editing and RNA-based therapeutics technology; 2) discuss the potential clinical application of genome editing for kidney-related diseases; and 3) discuss the potential clinical application of RNA-based drugs for common kidney diseases.

    Learning Pathway(s)

    • Genetic Diseases and Development

    Moderators

    • Opeyemi A. Olabisi, MD, PhD
    • Vishal Patel, MD

    Presentations

    • Check In and Continental Breakfast
      07:00 AM PDT – 08:00 AM PDT
      
    • Welcome and Opening Remarks
      08:00 AM PDT – 08:10 AM PDT
      
      • Vishal Patel, MD
    • Base Editing and Prime Editing: Technology and Toolbox for Correcting DNA Variants
      08:10 AM PDT – 08:40 AM PDT
      
      • Andrew Anzalone, MD, PhD
    • Targeting the Kidneys for Gene Therapy
      08:40 AM PDT – 09:10 AM PDT
      
      • Matthew H. Wilson, MD, PhD
    • Back to the Microbes: Searching for New and Diverse Gene-Editing Tools
      09:10 AM PDT – 09:40 AM PDT
      
      • Brian C. Thomas, PhD
    • Break
      09:40 AM PDT – 10:15 AM PDT
      
    • Delivery Approaches to Carry Genetic Cargo to Kidneys
      10:15 AM PDT – 10:45 AM PDT
      
      • Eun ji Chung, PhD
    • RNA Editing as a Novel Therapeutic Modality
      10:45 AM PDT – 11:15 AM PDT
      
      • Chikdu S. Shivalila, PhD
    • AAV Vector-Mediated Gene Therapy for Alport Syndrome
      11:15 AM PDT – 11:45 AM PDT
      
      • Hiroyuki Nakai, MD, PhD
    • Lunch (on your own)
      11:45 AM PDT – 01:00 PM PDT
      
    • CRISPR for the Treatment of Sickle Cell Disease
      01:00 PM PDT – 01:30 PM PDT
      
      • Alexis A. Thompson, MD, MPH
    • Gene Therapy for Podocytopathies
      01:30 PM PDT – 02:00 PM PDT
      
      • Moin A. Saleem, MD, MBBS, MBChB, PhD
    • RNA Interference in the Treatment of Kidney Stone Disease
      02:00 PM PDT – 02:30 PM PDT
      
      • John C. Lieske, MD, FASN
    • Break
      02:30 PM PDT – 03:00 PM PDT
      
    • RNAi Drugs to Treat Hypertension
      03:00 PM PDT – 03:30 PM PDT
      
      • Rhian Touyz, MD, MBChB, PhD
    • miRNA Therapeutics for Polycystic Kidney Disease
      03:30 PM PDT – 04:00 PM PDT
      
      • Edmund Chun Yu Lee, PhD
    • Antisense Oligonucleotide Therapy for APOL1-Mediated Kidney Disease
      04:00 PM PDT – 04:30 PM PDT
      
      • Peter J. Greasley, PhD
    • Antisense Oligonucleotide Therapy for Preeclampsia
      04:30 PM PDT – 05:00 PM PDT
      
      • S. Ananth Karumanchi, MD
    • Closing Remarks
      05:00 PM PDT – 05:10 PM PDT
      
      • Opeyemi A. Olabisi, MD, PhD